In my view I think a pokemon based off the early Americas religion would be awesome as well as something based off the mongals. Do you think it would work at all.

Xatu, anyone?

You’re going to need to be a lot more specific here.  As starting points, there’s nothing wrong with them, but either could be done extremely well or exceptionally badly – what exactly is the idea?  Also, “Early Americas” is very general – are we talking Great Plains?  Mexico?  Andes?  Amazon Basin?